Reference entry · Ghrelin mimetic hexapeptide
Hexarelin
Also known as: Examorelin · HEX
- Class
- Ghrelin mimetic hexapeptide
- Size
- 6 amino acids
- Primary targets (literature)
- GHS-R; cardiac tissue literature
- Regulatory context
- Not FDA-approved. Cardiac preclinical data are not therapeutic claims for catalog material.
Overview
Hexarelin is a potent hexapeptide ghrelin mimetic cited in GH-axis research and, separately, in rodent cardiac ischemia-reperfusion models. Cardioprotective preclinical findings do not establish clinical cardiac benefit.
Mechanism in research literature
High-affinity GHS-R agonism in pituitary models; preclinical cardiac literature explores ischemia-reperfusion endpoints with GHS-R expression in cardiac tissue.
Common research focus areas
- Potency reference in secretagogue class
- Cardiac ischemia-reperfusion rodent models
- Comparison vs. GHRP-2 and ipamorelin
- Distinct sequence from other hexapeptide GHRPs
Full literature roundup
Read the cited research summary
A potent hexapeptide ghrelin mimetic with GH-axis and cardioprotective research angles in animal models. Evidence and limitations.
Hexarelin research roundup · 5 minEvaluate catalog material
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