Reference entry · Ghrelin receptor (GHS-R) agonist
Ipamorelin
Also known as: Growth hormone secretagogue · selective GHRP
- Class
- Ghrelin receptor (GHS-R) agonist
- Size
- 5 amino acids
- Primary targets (literature)
- GHS-R / ghrelin receptor
- Regulatory context
- Not FDA-approved. Research-catalog secretagogue requiring batch identity confirmation.
Overview
Ipamorelin is a selective growth hormone secretagogue studied for relatively narrow hormonal release profiles compared with first-generation GHRPs. It is frequently paired in research discussions with GHRH analogs such as CJC-1295.
Mechanism in research literature
GHS-R agonism stimulates GH release through a pathway distinct from GHRH signaling. Comparative literature emphasizes reduced off-target hormonal activation vs. earlier GHRPs in standard assays.
Common research focus areas
- Selective GH release assays
- Combination research with CJC-1295 variants
- Pituitary cell and rodent PK/PD
- Sequence and purity for pentapeptide supply
Full literature roundup
Read the cited research summary
A selective growth hormone secretagogue studied in GH-axis research. Ghrelin receptor pharmacology, literature, and material quality.
Ipamorelin research roundup · 6 minEvaluate catalog material
- COA literacy — read batch documentation before comparing vendors.
- Peptide identity testing — why sequence confirmation matters beyond purity %.
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