Reference entry · Ghrelin mimetic hexapeptide
GHRP-6
Also known as: Growth hormone releasing peptide-6
- Class
- Ghrelin mimetic hexapeptide
- Size
- 6 amino acids
- Primary targets (literature)
- GHS-R / ghrelin receptor
- Regulatory context
- Not FDA-approved. Appetite-related preclinical findings are not human-use guidance.
Overview
GHRP-6 was among the first synthetic GHRPs characterized in ghrelin receptor research. Rodent literature documents appetite-stimulating effects alongside GH release — distinguishing it from more selective later compounds.
Mechanism in research literature
GHS-R agonism with prominent orexigenic effects in certain rodent assays, consistent with ghrelin-pathway biology in appetite research models.
Common research focus areas
- First-generation secretagogue reference
- Appetite endpoints in rodent models
- Comparative assays vs. GHRP-2 and hexarelin
- Historical vs. modern COA standards
Full literature roundup
Read the cited research summary
A first-generation GHRP widely cited in secretagogue research. GH-axis literature, noted appetite effects in models, and quality checks.
GHRP-6 research roundup · 5 minEvaluate catalog material
- COA literacy — read batch documentation before comparing vendors.
- Peptide identity testing — why sequence confirmation matters beyond purity %.
- How we vet sources — our score methodology for recommended vendors.