Reference entry · Synthetic tetrapeptide bioregulator
Cortagen
Also known as: Ala-Glu-Asp-His · AEDH tetrapeptide bioregulator
- Class
- Synthetic tetrapeptide bioregulator
- Size
- 4 amino acids
- Primary targets (literature)
- Adrenal cortex and stress-axis aging literature
- Regulatory context
- Not FDA-approved. Stress-axis preclinical data are not endocrine therapy guidance.
Overview
Cortagen is an Ala-Glu-Asp-His tetrapeptide bioregulator studied in adrenal cortex and stress-axis aging research. It is among the organ-targeted Khavinson peptides where catalog naming and sequence confirmation matter.
Mechanism in research literature
Literature proposes normalization of adrenal cortex gene expression and stress-hormone profiles in aging rodent models — distinct from pituitary GH-axis peptides.
Common research focus areas
- Adrenal cortex cell and tissue models
- Stress-axis and glucocorticoid aging endpoints
- Tetrapeptide sequence verification (AEDH)
- Separation from GH secretagogue research framing
Full literature roundup
Read the cited research summary
An Ala-Glu-Asp-His tetrapeptide bioregulator studied in adrenal cortex and stress-axis aging research. What the Khavinson literature describes — and how it differs from GH peptides.
Cortagen research roundup · 7 minEvaluate catalog material
- COA literacy — read batch documentation before comparing vendors.
- Peptide identity testing — why sequence confirmation matters beyond purity %.
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