Reference entry · Cosmetic hexapeptide
Argireline
Also known as: Acetyl hexapeptide-3 · Acetyl hexapeptide-8 · AH3
- Class
- Cosmetic hexapeptide
- Size
- 6 amino acids
- Primary targets (literature)
- SNAP-25 interaction literature
- Regulatory context
- Cosmetic ingredient — not FDA-approved as a drug. Injectable catalog argireline is outside typical cosmetic regulatory pathways.
Overview
Argireline is a widely used acetylated hexapeptide in cosmetic dermatology research, marketed as a topical SNAP-25 mimetic. It is among the most cited cosmetic peptides in formulation literature.
Mechanism in research literature
Proposed modulation of neuromuscular signaling via SNAP-25 pathway interference in cell and tissue models — cosmetic-science framing, not clinical neurology.
Common research focus areas
- Topical wrinkle and elasticity instrument studies
- SNAP-25 and SNARE-complex in vitro models
- Comparison with Snap-8 octapeptide analogs
- Hexapeptide identity and acetylation verification
Full literature roundup
Read the cited research summary
A widely used acetyl hexapeptide in cosmetic dermatology research. SNAP-25 mimetic literature, topical studies, and hexapeptide identity standards.
Argireline research roundup · 6 minEvaluate catalog material
- COA literacy — read batch documentation before comparing vendors.
- Peptide identity testing — why sequence confirmation matters beyond purity %.
- How we vet sources — our score methodology for recommended vendors.