Reference entry · IGF-1Ec-derived synthetic E-peptide (catalog) / splice variant (literature)
MGF
Also known as: Mechano Growth Factor · IGF-1Ec E-peptide · IGF-1 splice variant
- Class
- IGF-1Ec-derived synthetic E-peptide (catalog) / splice variant (literature)
- Size
- Typically 24 amino acids (synthetic catalog form)
- Primary targets (literature)
- Satellite cell and repair literature; IGF-axis biology
- Regulatory context
- Not FDA-approved. No validated human therapeutic label. WADA-related scrutiny applies to IGF-1 pathway peptides in sport.
Overview
MGF in literature refers to IGF-1Ec, an IGF-1 splice variant up-regulated after muscle stress. Catalog MGF usually means a synthetic 24-mer E-peptide — not proven as an isolated endogenous product.
Mechanism in research literature
Proposed roles in satellite cell activation and cell survival in preclinical models. Synthetic E-peptide effects may occur independently of full IGF-1R agonism in some assays — literature remains debated.
Common research focus areas
- IGF-1 gene splicing after mechanical muscle load
- Synthetic E-peptide proliferation assays vs. endogenous isoform
- Distinction from IGF-1 LR3 and PEG-MGF
- Sequence and species nomenclature verification
Full literature roundup
Read the cited research summary
The IGF-1Ec splice variant and its synthetic E-peptide — satellite cell literature, naming confusion, and why catalog MGF requires sequence proof.
MGF research roundup · 5 minEvaluate catalog material
- COA literacy — read batch documentation before comparing vendors.
- Peptide identity testing — why sequence confirmation matters beyond purity %.
- How we vet sources — our score methodology for recommended vendors.