Reference entry · Synthetic cyclic melanocortin agonist
Melanotan II
Also known as: MT-II · Melanotan 2 · Afamelanotide-related melanocortin agonist class
- Class
- Synthetic cyclic melanocortin agonist
- Size
- 7 amino acids (cyclic heptapeptide)
- Primary targets (literature)
- MC1R, MC3R, MC4R, MC5R (melanocortin receptors)
- Regulatory context
- Not FDA-approved. Catalog melanotan II is research-use-only material; tanning or cosmetic use contexts are outside this library's scope.
Overview
Melanotan II is a synthetic cyclic heptapeptide melanocortin agonist studied in melanogenesis, pigmentation, and central melanocortin signaling research. It is chemically related to bremelanotide (PT-141) but is not an FDA-approved drug product.
Mechanism in research literature
Melanocortin receptor activation at MC1R drives melanogenesis research endpoints; MC4R engagement appears in appetite, energy, and behavioral pharmacology literature alongside pigmentation studies.
Common research focus areas
- Melanogenesis and MC1R pigmentation models
- Melanocortin behavioral pharmacology (MC4R)
- Chemical relationship to PT-141 / bremelanotide
- Sequence and cyclic structure verification
Full literature roundup
Read the cited research summary
A synthetic melanocortin agonist studied in pigmentation and central receptor pharmacology. Literature scope, MC1R context, and material verification.
Melanotan II research roundup · 7 minEvaluate catalog material
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