Reference entry · α-MSH-derived tripeptide
KPV
Also known as: Lys-Pro-Val · α-MSH tripeptide fragment
- Class
- α-MSH-derived tripeptide
- Size
- 3 amino acids
- Primary targets (literature)
- MC1R-related literature; NF-κB and inflammatory signaling
- Regulatory context
- Not FDA-approved. Catalog KPV is research-use-only; no therapeutic claims attach to undocumented material.
Overview
KPV is a C-terminal tripeptide fragment of alpha-melanocyte-stimulating hormone studied in gut inflammation, skin inflammation, and immune-modulation research. Small size makes identity testing straightforward when documentation is provided.
Mechanism in research literature
Preclinical literature links KPV to reduced inflammatory cytokine signaling in colitis and dermatitis models, often framed as melanocortin-pathway modulation without full α-MSH pharmacology.
Common research focus areas
- Colitis and intestinal inflammation rodent models
- Skin inflammation and keratinocyte assays
- Tripeptide identity and salt-form specification
- Comparison with broader melanocortin peptides
Full literature roundup
Read the cited research summary
A tripeptide fragment of alpha-MSH studied in gut and skin inflammation models. What preclinical literature reports within a research-use-only frame.
KPV research roundup · 8 minEvaluate catalog material
- COA literacy — read batch documentation before comparing vendors.
- Peptide identity testing — why sequence confirmation matters beyond purity %.
- How we vet sources — our score methodology for recommended vendors.