Reference entry · Renin-angiotensin system peptide
Angiotensin (1-7)
Also known as: Ang-(1-7) · Mas receptor agonist peptide
- Class
- Renin-angiotensin system peptide
- Size
- 7 amino acids
- Primary targets (literature)
- Mas receptor (primary literature); ACE2-generated metabolite
- Regulatory context
- Investigational in most therapeutic contexts — not FDA-approved as a catalog drug. Research material requires batch identity confirmation.
Overview
Angiotensin (1-7) is a heptapeptide metabolite of the renin-angiotensin system studied as a counter-regulatory arm opposing Ang II signaling, with cardiovascular and fibrosis research literature.
Mechanism in research literature
Mas receptor activation modulates vasodilation, anti-fibrotic, and anti-inflammatory pathways in preclinical models — distinct from ACE inhibition or Ang II receptor blockade.
Common research focus areas
- Mas receptor pharmacology and knockout models
- Cardiovascular and pulmonary fibrosis research
- ACE2–Ang-(1-7) axis in injury models
- Heptapeptide identity and acetate salt specification
Full literature roundup
Read the cited research summary
A heptapeptide arm of the renin-angiotensin system studied via Mas receptor signaling. Cardiovascular and fibrosis research within an RUO frame.
Angiotensin (1-7) research roundup · 6 minEvaluate catalog material
- COA literacy — read batch documentation before comparing vendors.
- Peptide identity testing — why sequence confirmation matters beyond purity %.
- How we vet sources — our score methodology for recommended vendors.